2023
Trends in Microbiology
Ecology of the respiratory tract microbiome
Ana Elena Pérez-Cobas, Jerónimo Rodríguez-Beltrán, Fernando Baquero, 
Teresa M. Coque

Read the paper >

Biology
Bacterial Subcellular Architecture, Structural Epistasis, and Antibiotic Resistance

 

Read the paper >

2022
Nature Ecology and Evolution
Within-patient evolution of plasmid-mediated antimicrobial resistance

J DelaFuente, L Toribio-Celestino, A Santos-Lopez, R Leon-Sampedro, A Alonso-del Valle, C Costas, M Hernandez-Garcia, L Cui, Jeronimo Rodriguez-Beltran, D Bikard, R Canton, A San Millan

Read the paper >

Philosphical Transactions B
Translational demand is not a major source of plasmid-associated fitness costs​

Jerónimo Rodríguez-Beltrán, Ricardo León-Sampedro, Paula Ramiro Martínez, Carmen de la Vega, Fernando Baquero, Bruce R. Levin, Álvaro San Millán

Read the paper >

Antibiotics
Inactivation of a New Potassium Channel Increases Rifampicin Resistance and Induces Collateral Sensitivity to Hydrophilic Antibiotics in Mycobacterium smegmatis

Thi Thuy Do, Jerónimo Rodríguez-Beltran, Esmeralda Cebrián-Sastre, Alexandro Rodríguez-Rojas, Alfredo Castañeda-García, Jesús Blázquez

Read the paper >

2021
Nature Reviews in Microbiology
Beyond horizontal gene transfer: the role of plasmids in bacterial evolution

Jerónimo Rodríguez-Beltrán, Javier DelaFuente, Ricardo Leon-Sampedro, R Craig MacLean, Alvaro San Millan

Read the paper >

Frontiers in Microbiology
Allogenous Selection of Mutational Collateral Resistance: Old Drugs Select for New Resistance Within Antibiotic Families​

Fernando Baquero, José L. Martínez, Ângela Novais, Jerónimo Rodríguez-Beltrán, Laura Martínez-García, Teresa M. Coque and Juan Carlos Galán

Read the paper >

PLoS Biology
The bacterial capsule is a gatekeeper for mobile DNA​

Alfonso Santos-López, Jerónimo Rodríguez-Beltrán, Álvaro San Millán

Read the paper >

Nature Microbiology
Pervasive transmission of a carbapenem resistance plasmid in the gut microbiota of hospitalized patients​

Ricardo León-Sampedro, Javier DelaFuente, Cristina Díaz-Agero, Thomas Crellen, Patrick Musicha, Jerónimo Rodríguez-Beltrán, Carmen de la Vega, Marta Hernández-García, Nieves López-Fresneña, Patricia Ruiz-Garbajosa, Rafael Cantón, Ben S Cooper, Álvaro San Millán

Read the paper >

Nature Communications
Variability of plasmid fitness effects contributes to plasmid persistence in bacterial communities​

Aida Alonso-del Valle, Ricardo León-Sampedro, Jerónimo Rodríguez-Beltrán, Javier DelaFuente, Marta Hernández-García, Patricia Ruiz-Garbajosa, Rafael Cantón, Rafael Peña-Miller, Alvaro San Millán

Read the paper >

eLife
Collateral sensitivity associated with antibiotic resistance plasmids​

Cristina Herencias, Jerónimo Rodríguez-Beltrán, Ricardo León-Sampedro, Aida Alonso-del Valle, Jana Palkovičová, Rafael Cantón, Álvaro San Millán

Read the paper >

Clinical Microbiology Reviews
Evolutionary pathways and trajectories in antibiotic resistance​

Fernando Baquero, Jose L Martinez, V F. Lanza, J Rodríguez-Beltrán, JC Galán, A San Millán, R Cantón, TM Coque

Read the paper >

Plasmid
Quantifying plasmid dynamics using single-cell microfluidics and image bioinformatics

JCR Hernandez-Beltran, J Rodríguez-Beltrán, A San Millán, R Peña-Miller, A Fuentes-Hernández

Read the paper >

2020
Antibiotics
Detection of Low-Level Fosfomycin-Resistant Variants by Decreasing Glucose-6-Phosphate Concentration in Fosfomycin Susceptibility Determination ​

Guillermo Martín-Gutiérrez, Fernando Docobo-Pérez, Jose Manuel Rodríguez-Martínez, Alvaro Pascual, Jesús Blázquez, Jeronimo Rodriguez-Beltrán

Read the paper >

PNAS
Genetic dominance governs the evolution and spread of mobile genetic elements in bacteria​

Jerónimo Rodríguez-Beltrán, Vidar Sørum, Macarena Toll-Riera, Carmen de la Vega, Rafael Peña-Miller, Álvaro San Millán

Read the paper >

Horizontal Gene Transfer
Methods to study fitness and compensatory adaptation in plasmid-carrying bacteria

Javier DelaFuente, Jeronimo Rodriguez-Beltran, Alvaro San Millan

Read the paper >

2019
Journal of Antimicrobial Chem.
N-acetylcysteine blocks SOS induction and mutagenesis produced by fluoroquinolones in Escherichia coli​

Ana I Rodríguez-Rosado, Estela Ynés Valencia, Alexandro Rodríguez-Rojas, Coloma Costas, Rodrigo S Galhardo, Jerónimo Rodríguez-Beltrán, Jesús Blázquez

Read the paper >